A Minimally Invasive Therapy

Amongst the most popular advances in medicine are those that involve minimally invasive procedures. Key benefits can include avoiding major surgery and associated morbidity risks, the use of local anesthesia in place of general anesthesia, shorter recovery times, and less reliance upon high dependency hospital units. Elk’s GDEPT therapy and subsequent re-cementation strategy is completed via a series of direct injections into the joint space under active visual guidance. The GDEPT strategy is a platform technology with the potential to be applied to all joints that develop aseptic loosening, including hips, knees and shoulders.


The only current treatment for aseptic loosening is revision surgery, a major surgical intervention where the existing orthopaedic implant is removed, the synovial-like tissue removed and a new larger prosthesis fitted. An alternative minimally invasive treatment is required. 

Elk’s therapy for repairing aseptically loosened hip and knee prostheses has successfully completed Phase I clinical trials at Leiden University Medical Center in the Netherlands. In the Phase I trial, a majority of patients experienced a reduction in pain, whilst some regained the ability to walk, having been bedridden.